CDC25 Phosphatase Inhibitor I
CAS No. 396073-89-5
CDC25 Phosphatase Inhibitor I ( BN-82002;CDC25 Phosphatase Inhibitor I; PTP Inhibitor XX; )
Catalog No. M19377 CAS No. 396073-89-5
BN82002 is a synthetic inhibitor of CDC25 phophatases.
Purity : 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 80 | In Stock |
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10MG | 110 | In Stock |
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25MG | 200 | In Stock |
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50MG | 335 | In Stock |
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100MG | 500 | In Stock |
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200MG | Get Quote | In Stock |
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500MG | Get Quote | In Stock |
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1G | Get Quote | In Stock |
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Biological Information
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Product NameCDC25 Phosphatase Inhibitor I
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NoteResearch use only, not for human use.
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Brief DescriptionBN82002 is a synthetic inhibitor of CDC25 phophatases.
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DescriptionBN-82002, also known as CDC25 Phosphatase Inhibitor I, is a cell-permeable ortho-hydroxybenzylamino compound that displays anti-tumor properties. BN-82002 acts as a potent, selective, and irreversible inhibitor of CDC25 phosphatase family (IC50 = 2.4, 3.9, 6.3, 5.4, and 4.6 μM for 25A, 25B2, 25B3, 25C, and 25C-cat, respectively). BN82002 inhibits the phosphatase activity of recombinant human CDC25A, B, and C in vitro. It impairs the proliferation of tumoral cell lines and increases cyclin-dependent kinase 1 inhibitory tyrosine phosphorylation. In synchronized HeLa cells, BN82002 delays cell cycle progression at G1-S, in S phase and at the G2-M transition.
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SynonymsBN-82002;CDC25 Phosphatase Inhibitor I; PTP Inhibitor XX;
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PathwayMetabolic Enzyme/Protease
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TargetPhosphatase
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RecptorCDC25A;CDC25B2;CDC25B3;CDC25C;CDC25C-cat
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Research Area——
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Indication——
Chemical Information
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CAS Number396073-89-5
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Formula Weight359.42
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Molecular FormulaC19H25N3O4
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Purity98%
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SolubilityDMSO : ≥ 150 mg/mL; 417.34 mM
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SMILESOc1c(cc(cc1OC)N(C)C)CN(C)CCc2ccc(cc2)[N+]([O-])=O
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Chemical NamePhenol, 4-(dimethylamino)-2-methoxy-6-((methyl(2-(4-nitrophenyl)ethyl)amino)methyl)-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Brezak MC, et al. A novel synthetic inhibitor of CDC25 phosphatases: BN82002. Cancer Res. 2004 May 1;64(9):3320-5.
molnova catalog
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